Harvey DJ. Absorption, distribution, and biotransformation of the cannabinoids. Effects of short-term cannabidiol treatment on response to social stress in subjects at clinical high risk of developing psychosis. Some sedative medications include benzodiazepines, pentobarbital , phenobarbital , secobarbital , thiopental , fentanyl , morphine, propofol , and others.Tacrolimus Tacrolimus is changed and broken down by the body. Cannabidiol might decrease how quickly the body breaks down tacrolimus.